A man affected by a certain disease marries a | vedclass

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(B) In this scenario,the father is affected and passes the trait to all his daughters but none of his sons.Since the father passes his $X$ chromosome

Vedclass · Accepted Answer

Sex-linked dominant

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(B) In this scenario,the father is affected and passes the trait to all his daughters but none of his sons.Since the father passes his $X$ chromosome to all his daughters and his $Y$ chromosome to all his sons,the trait must be located on the $X$ chromosome.Because all daughters are affected,the trait must be dominant,as a single copy of the dominant allele on the $X$ chromosome inherited from the father is sufficient to express the disease in the daughters.If it were recessive,the daughters would be carriers (assuming the mother is normal),but they would not necessarily show the disease unless the mother was also a carrier. Thus,the pattern of inheritance is $X$-linked dominant.

$A$ man affected by a certain disease marries a normal woman. They have $8$ children ($3$ daughters and $5$ sons). All the daughters suffer from their father's disease,but none of the sons are affected. What type of inheritance can you suggest for this disease?

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