If both parents are carriers of thalassemia,w | vedclass

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(C) Thalassemia is an autosomal recessive disorder. Let the normal allele be represented by '$A$' and the recessive disease-causing allele by '$a$'.Si

Vedclass · Accepted Answer

$25\%$

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(C) Thalassemia is an autosomal recessive disorder. Let the normal allele be represented by '$A$' and the recessive disease-causing allele by '$a$'.Since both parents are carriers,their genotypes are '$Aa$'.When we perform a cross between two carriers $(Aa 	imes Aa)$:The possible offspring genotypes are:$AA$ (Normal - $25\%$)$Aa$ (Carrier - $50\%$)$aa$ (Affected - $25\%$)Therefore,the probability of having an affected child $(aa)$ is $25\%$.

If both parents are carriers of thalassemia,which is an autosomal recessive disorder,what is the probability of having an affected child?

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