What will happen if the secretion of parietal | vedclass

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(C) The parietal cells (also known as oxyntic cells) of the gastric glands are responsible for the secretion of $HCl$ (hydrochloric acid) and Castle's

Vedclass · Accepted Answer

In the absence of $HCl$ secretion,inactive pepsinogen will not be converted into the active enzyme pepsin.

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(C) The parietal cells (also known as oxyntic cells) of the gastric glands are responsible for the secretion of $HCl$ (hydrochloric acid) and Castle's intrinsic factor.$HCl$ plays a crucial role in the stomach by providing an acidic medium ($pH$ $1.8$) which is necessary for the activation of the inactive proenzyme pepsinogen into the active proteolytic enzyme pepsin.If the secretion of parietal cells is blocked,$HCl$ will not be produced.Consequently,the conversion of inactive pepsinogen to active pepsin will be inhibited,leading to impaired protein digestion in the stomach.

What will happen if the secretion of parietal cells of the gastric glands is blocked by an inhibitor?

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