C_6H_6 xrightarrow[AlCl_3]{(CH_3)_2CHCOCl} xr | vedclass

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Question

(B) The synthesis of Ibuprofen involves the following steps:$1$. Friedel-Crafts acylation of benzene with isobutyryl chloride to form isobutyrophenone

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(B) The synthesis of Ibuprofen involves the following steps:$1$. Friedel-Crafts acylation of benzene with isobutyryl chloride to form isobutyrophenone.$2$. Clemmensen reduction of the ketone to form isobutylbenzene.$3$. Friedel-Crafts acylation of isobutylbenzene with acetyl chloride to form $4$-isobutylacetophenone.$4$. Cyanohydrin formation followed by reduction with $Red \ P + HI$ to convert the acetyl group into a propionic acid group,yielding $2-(4-	ext{isobutylphenyl})	ext{propanoic acid}$,which is Ibuprofen.The correct structure is shown in option $B$.

$C_6H_6$ $\xrightarrow[AlCl_3]{(CH_3)_2CHCOCl}$ $\xrightarrow[\text{reduction}]{\text{Clemmensen}}$ $\xrightarrow[AlCl_3]{CH_3COCl}$ $\xrightarrow[\text{Red } P + HI]{H_3O^{\oplus}} (\text{Ibuprofen})$
Ibuprofen is

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$C_6H_6$ $\xrightarrow[AlCl_3]{(CH_3)_2CHCOCl}$ $\xrightarrow[\text{reduction}]{\text{Clemmensen}}$ $\xrightarrow[AlCl_3]{CH_3COCl}$ $\xrightarrow[\text{Red } P + HI]{H_3O^{\oplus}} (\text{Ibuprofen})$Ibuprofen is