Which of the following compounds will react w | vedclass

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Question

(A) Alcohols and phenols react with acid chlorides $(RCOCl)$ in the presence of a base (like pyridine) to form esters. The reaction is: $R-OH + R'-COC

Vedclass · Accepted Answer

$C_6H_5OH$

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(A) Alcohols and phenols react with acid chlorides $(RCOCl)$ in the presence of a base (like pyridine) to form esters. The reaction is: $R-OH + R'-COCl \xrightarrow{	ext{pyridine}} R'-COOR + HCl$. Among the given options,$C_6H_5OH$ (phenol) is an alcohol/phenol derivative that can undergo this reaction (acylation) to form an ester (phenyl ester). $CH_3COOH$ is a carboxylic acid and $CH_3COCl$ is an acid chloride itself,so they do not form esters with acid chlorides.

Which of the following compounds will react with an acid chloride to form an ester?

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