Which of the following statements is $NOT$ correct?

  • A
    Insulin in humans is synthesized as proinsulin.
  • B
    Proinsulin contains an extra peptide called the $C$-peptide.
  • C
    Active insulin consists of $A$ and $B$ chains linked together by hydrogen bonds.
  • D
    Genetically engineered insulin is produced in $E. coli$.

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