(C) In human development,the heart is the first organ to develop. The heart begins to form during the $4^{th}$ week of pregnancy (approximately $21-22

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At the fourth week of pregnancy

(C) In human development,the heart is the first organ to develop. The heart begins to form during the $4^{th}$ week of pregnancy (approximately $21-22$ days after fertilization). By the end of the first month of pregnancy,the heart is formed and begins to beat.