Hemophilia is more common in males than in fe | vedclass

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(D) Hemophilia is a sex-linked recessive disorder caused by a mutation in genes located on the $X$ chromosome.In females,there are two $X$ chromosomes

Vedclass · Accepted Answer

It is an $X$-linked recessive disorder.

Vedclass · Answer

(D) Hemophilia is a sex-linked recessive disorder caused by a mutation in genes located on the $X$ chromosome.In females,there are two $X$ chromosomes $(XX)$. For a female to be affected,she must inherit the recessive gene on both $X$ chromosomes $(X^hX^h)$.In males,there is only one $X$ chromosome $(XY)$. If a male inherits the recessive gene on his single $X$ chromosome $(X^hY)$,he will express the disorder.Therefore,males are more frequently affected because they only require one copy of the defective gene to manifest the disease,whereas females require two.

Hemophilia is more common in males than in females because...

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