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(A) The semi-conservative nature of $DNA$ replication was experimentally proven by Matthew Meselson and Franklin Stahl in $1958$.They used the bacteri

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$E. coli$

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(A) The semi-conservative nature of $DNA$ replication was experimentally proven by Matthew Meselson and Franklin Stahl in $1958$.They used the bacterium $Escherichia coli$ $(E. coli)$ for their experiments.By growing $E. coli$ in a medium containing $^{15}N$ (a heavy isotope of nitrogen) and then transferring it to a medium containing $^{14}N$ (a lighter isotope),they observed the density of the $DNA$ using cesium chloride $(CsCl)$ density gradient centrifugation.The results showed that after one generation,the $DNA$ was a hybrid of $^{15}N$ and $^{14}N$,confirming the semi-conservative model of replication.

Which bacteria provided the first evidence that $DNA$ replication is semi-conservative?

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