In gene therapy,which cells of the patient ar | vedclass

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(A) Gene therapy is a technique used to correct a genetic defect that has been diagnosed in a child or embryo. In the first clinical gene therapy tria

Vedclass · Accepted Answer

Lymphocytes

Vedclass · Answer

(A) Gene therapy is a technique used to correct a genetic defect that has been diagnosed in a child or embryo. In the first clinical gene therapy trial conducted in $1990$ for Adenosine Deaminase $(ADA)$ deficiency,lymphocytes were extracted from the patient's blood. These lymphocytes were grown in a culture medium outside the body. $A$ functional $ADA$ cDNA was then introduced into these lymphocytes using a retroviral vector. Finally,these genetically engineered lymphocytes were returned to the patient. Therefore,the correct answer is Lymphocytes.

Column-$I$	Column-$II$
$(1)$ Diabetes	$(a)$ $ADA$
$(2)$ Enzyme replacement therapy	$(b)$ Alpha-lactalbumin
$(3)$ Emphysema	$(c)$ Insulin
$(4)$ Rosie cow	$(d)$ $\alpha-1$-Antitrypsin
	$(e)$ Typhoid

In gene therapy,which cells of the patient are cultured?

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Match the columns:

Column-$I$ Column-$II$

$(1)$ Diabetes $(a)$ $ADA$

$(2)$ Enzyme replacement therapy $(b)$ Alpha-lactalbumin

$(3)$ Emphysema $(c)$ Insulin

$(4)$ Rosie cow $(d)$ $\alpha-1$-Antitrypsin

$(e)$ Typhoid

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