A : Non-competitive inhibitors have no effect | vedclass

Name: Exam Paper Generator | JEE NEET Paper Generator | Vedclass
Brand: Vedclass
Rating: 5 (35 reviews)

Question

(D) Non-competitive inhibitors bind to an allosteric site (a site other than the active site) on the enzyme,which changes the conformation of the enzy

Vedclass · Accepted Answer

Both Assertion and Reason are incorrect.

Vedclass · Answer

(D) Non-competitive inhibitors bind to an allosteric site (a site other than the active site) on the enzyme,which changes the conformation of the enzyme such that the active site becomes less effective. This binding does not prevent substrate binding but reduces the catalytic rate,thereby decreasing the maximum velocity $(V_{max})$ of the reaction. Therefore,the Assertion is incorrect. The Reason is also incorrect because,in non-competitive inhibition,the inhibitor and substrate bind at different sites,not the same site. Thus,both Assertion and Reason are incorrect.

$A$ : Non-competitive inhibitors have no effect on $V_{max}$.
$R$ : In non-competitive inhibition,inhibitor and substrate bind at same sites on the enzyme.

Similar Questions

The first enzyme was discovered in . . . . . . .

Which of the following statements is correct regarding enzymes?

Enzymes,vitamins,and hormones can be classified into a single category of biological chemicals because all of these

The specific region of an enzyme where the substrate binds is known as the ...... .

Formation of Enzyme-substrate complex $(ES)$ is the first step in the catalysed reactions. Describe the other steps until the formation of the product.

Vedclass Test Series

Exam Paper Generator

Online Exam Module

$A$ : Non-competitive inhibitors have no effect on $V_{max}$.$R$ : In non-competitive inhibition,inhibitor and substrate bind at same sites on the enzyme.