State the path of H^+ for the synthesis of AT | vedclass

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Question

(C) In the process of oxidative phosphorylation,$ATP$ synthase consists of two major components: $F_0$ and $F_1$.$F_0$ is an integral membrane protein

Vedclass · Accepted Answer

Intermembrane space $\rightarrow F_0 \rightarrow$ Matrix

Vedclass · Answer

(C) In the process of oxidative phosphorylation,$ATP$ synthase consists of two major components: $F_0$ and $F_1$.$F_0$ is an integral membrane protein complex that forms a channel through which protons $(H^+)$ cross the inner mitochondrial membrane.$F_1$ is a peripheral membrane protein complex that projects into the matrix and contains the site for $ATP$ synthesis.Protons accumulate in the intermembrane space due to the electron transport chain,creating a proton gradient.These protons flow back into the matrix through the $F_0$ channel,which provides the energy for $F_1$ to catalyze the synthesis of $ATP$ from $ADP$ and inorganic phosphate $(\Pi)$.Therefore,the path of $H^+$ is: Intermembrane space $\rightarrow F_0 \rightarrow$ Matrix.

State the path of $H^+$ for the synthesis of $ATP$ by $ATP$ synthase.

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