Which of the following treatments cannot comp | vedclass

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(D) Step $1$: $ADA$ deficiency (Adenosine Deaminase deficiency) is a genetic disorder caused by the deletion of the gene for adenosine deaminase.Step

Vedclass · Accepted Answer

Both $A$ and $B$

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(D) Step $1$: $ADA$ deficiency (Adenosine Deaminase deficiency) is a genetic disorder caused by the deletion of the gene for adenosine deaminase.Step $2$: Enzyme replacement therapy involves the periodic injection of functional $ADA$ into the patient. It is not a permanent cure because the patient's own cells do not produce the enzyme.Step $3$: Bone marrow transplantation can be curative if performed early, but it is not always successful due to the difficulty in finding a suitable donor and the risk of rejection.Step $4$: Gene therapy is considered a potential permanent cure because it involves introducing functional $ADA$ $cDNA$ into the patient's lymphocytes, which are then cultured and returned to the patient.Step $5$: Since both enzyme replacement therapy and bone marrow transplantation are not completely curative, the correct option is $D$.

Which of the following treatments cannot completely cure $ADA$ deficiency?

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