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(C) The semiconservative nature of $DNA$ replication was first experimentally demonstrated by Matthew Meselson and Franklin Stahl in $1958$.They used

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Meselson and Stahl

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(C) The semiconservative nature of $DNA$ replication was first experimentally demonstrated by Matthew Meselson and Franklin Stahl in $1958$.They used $E. coli$ bacteria and grew them in a medium containing heavy nitrogen isotope $^{15}N$ for several generations.Then,they transferred the cells to a medium containing normal nitrogen isotope $^{14}N$.By using cesium chloride $(CsCl)$ density gradient centrifugation,they observed that the $DNA$ molecules had an intermediate density,which confirmed that each new $DNA$ molecule consists of one old strand and one newly synthesized strand.

$DNA$ replication of semiconservative type was first demonstrated by

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