How does the presence of an enzyme affect the activation energy of a reaction?

The enzyme invertase hydrolyses

Study the following statements:
$(a)$ The substrate binds to the active site of the enzyme.
$(b)$ Enzymes isolated from thermophilic organisms get denatured at $50^{\circ}C$.
$(c)$ The active site of the enzyme breaks the chemical bonds of the product.
$(d)$ Prosthetic groups are tightly bound to the apoenzyme.
Select the option which includes all correct statements:

Demonstrate the mechanism of action of transaminases.

Most of the biochemical reactions differ from those occurring in the non-living world in:

Select the correct option for the active site.