The formation of Acetyl-CoA from Pyruvic acid | vedclass

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Question

(D) The conversion of $Pyruvic$ $acid$ $(3C)$ into $Acetyl-CoA$ $(2C)$ occurs in the mitochondrial matrix. This process is catalyzed by the $Pyruvate$

Vedclass · Accepted Answer

Oxidative decarboxylation

Vedclass · Answer

(D) The conversion of $Pyruvic$ $acid$ $(3C)$ into $Acetyl-CoA$ $(2C)$ occurs in the mitochondrial matrix. This process is catalyzed by the $Pyruvate$ $dehydrogenase$ complex. During this reaction,one molecule of $CO_2$ is released (decarboxylation) and $NAD^+$ is reduced to $NADH + H^+$ (oxidation). Therefore,this step is known as $Oxidative$ $decarboxylation$.

The formation of $Acetyl-CoA$ from $Pyruvic$ $acid$ is a result of .....

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