The 'one gene, one enzyme' hypothesis was proposed by . . . . . . .

Statement $I :$ The codon $'AUG'$ codes for methionine and phenylalanine.
Statement $II :$ $'AAA'$ and $'AAG'$ both codons code for the amino acid lysine.
In the light of the above statements,choose the correct answer from the options given below.

$A$: Wobbling reduces the number of $tRNAs$ required for polypeptide synthesis.
$R$: It increases the effect of code degeneracy.

Choose the correct pair.

Column-$I$	Column-$II$
$A$. $AUG$	$1$. Phenylalanine
$B$. $UAA$	$2$. Methionine
$C$. $UUU$	$3$. Tryptophan
$D$. $UGG$	$4$. Stop

There is only one possible sequence of amino acids when deduced from a given nucleotide sequence. However,multiple nucleotide sequences can be deduced from a single amino acid sequence. Explain this phenomenon.

The genetic code was deciphered by chemical synthesis of trinucleotides by: