The semi-conservative replication of DNA was | vedclass

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(C) The semi-conservative replication of $DNA$ was experimentally proven by Matthew Meselson and Franklin Stahl in $1958$.They used the bacterium $Esc

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$Escherichia$ $coli$

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(C) The semi-conservative replication of $DNA$ was experimentally proven by Matthew Meselson and Franklin Stahl in $1958$.They used the bacterium $Escherichia$ $coli$ $(E. coli)$ for their experiments.They grew $E. coli$ in a medium containing $^{15}N$ (a heavy isotope of nitrogen) for many generations to incorporate it into the $DNA$,and then transferred it to a medium containing $^{14}N$ (a lighter isotope).By analyzing the density of the $DNA$ using cesium chloride $(CsCl)$ density gradient centrifugation,they observed that the $DNA$ molecules were hybrids of both isotopes,confirming the semi-conservative model of replication.

The semi-conservative replication of $DNA$ was proven in:

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