During transcription,the holoenzyme RNA polym | vedclass

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(D) During the initiation of transcription in eukaryotes,the $RNA$ polymerase holoenzyme recognizes and binds to a specific promoter sequence on the $

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$TATA$ box

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(D) During the initiation of transcription in eukaryotes,the $RNA$ polymerase holoenzyme recognizes and binds to a specific promoter sequence on the $DNA$ template.This specific sequence is rich in $Adenine$ and $Thymine$ bases and is known as the $TATA$ box (or $Goldberg-Hogness$ box).It is located approximately $25$ to $30$ base pairs upstream of the transcription start site.The binding of $RNA$ polymerase to this site creates a characteristic 'saddle' or 'bubble' structure,which facilitates the unwinding of the $DNA$ double helix to initiate transcription.

During transcription,the holoenzyme $RNA$ polymerase binds to the $DNA$ strand. It forms a structure resembling a saddle at a specific site on the $DNA$. This sequence is called .....

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