Which of the following factors shift the $HbO_2$ dissociation curve to the right?

  • A
    $(a)$ Increase in $PCO_2$
  • B
    $(b)$ Decrease in temperature
  • C
    $(c)$ Increase in $H^+$ (decrease in $pH$)
  • D
    $(d)$ Decrease in $2,3-DPG$ (diphosphoglyceric acid)

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