A mutation caused by the insertion or deletio | vedclass

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(D) mutation that involves the addition or deletion of one or more nucleotides in a $DNA$ sequence is known as a $Frameshift$ mutation. This occurs be

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Frameshift

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(D) mutation that involves the addition or deletion of one or more nucleotides in a $DNA$ sequence is known as a $Frameshift$ mutation. This occurs because the genetic code is read in triplets (codons). Adding or removing a nucleotide shifts the entire reading frame of the mRNA sequence from the point of mutation onwards,resulting in a completely different sequence of amino acids in the protein product.

Column-$I$	Column-$II$
$(1)$ Lethal mutation	$(a)$ Mutation caused by external factors
$(2)$ Spontaneous mutation	$(b)$ They are metabolic errors
$(3)$ Induced mutation	$(c)$ As a result the mutant dies
$(4)$ Biochemical mutation	$(d)$ Most of the mutations occurring in nature are of this type

$A$ mutation caused by the insertion or deletion of a nucleotide is called ........

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