The action potential of a neuron is generated by which of the following?

  • A
    $Na^+$
  • B
    $K^+$
  • C
    $Ca^{++}$
  • D
    $Cl^-$

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On application of a stimulus on the axonal membrane,

Assertion: The imbalance in concentration of $Na^+$,$K^+$ and proteins generates resting potential.
Reason: To maintain the unequal distribution of $Na^+$ and $K^+$,the neurons use electrical energy.

The nerve fibre in its resting stage is

Resting membrane potential is maintained by

Which of the following statement/s is/are correct with respect to generation and conduction of nerve impulse?
i. The resting potential difference is $-70 \text{ mV}$.
ii. The voltage-gated $Na^{+}$ and $K^{+}$ channels operate together and are self-closing.
iii. At the peak of action potential,the potential difference rises to $+30$ to $+60 \text{ mV}$.
iv. In medullated nerve fibre,the action potential is conducted as a wave of membrane depolarization.
v. The resting potential is maintained by the closure of gated channels of $Na^{+}$ and $K^{+}$.

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