Assertion : Activity of an enzyme is pH depen | vedclass

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Question

(B) The activity of an enzyme is highly $pH$ dependent because enzymes are proteins,and their tertiary structure (which determines their active site)

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If both Assertion and Reason are correct but Reason is not a correct explanation of the Assertion.

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(B) The activity of an enzyme is highly $pH$ dependent because enzymes are proteins,and their tertiary structure (which determines their active site) is maintained by ionic and hydrogen bonds that are sensitive to $pH$ changes. When the $pH$ changes,these bonds break,leading to denaturation of the enzyme and loss of catalytic activity. While it is true that $pH$ can affect the solubility of proteins (as they are least soluble at their isoelectric point),this is not the primary reason why enzyme activity is $pH$ dependent. Therefore,both statements are correct,but the reason does not explain the assertion.

Assertion : Activity of an enzyme is $pH$ dependent.
Reason : Change in $pH$ affects the solubility of enzyme in water.

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Assertion : Activity of an enzyme is $pH$ dependent.Reason : Change in $pH$ affects the solubility of enzyme in water.