Biotechnology is the modern branch of biology which deals with

Which of the following is correctly matched?

Match the Column-$I$ with Column-$II$:

Column-$I$	Column-$II$
$(a)$ $K$.$C$. Mehta	$(i)$ Fluid mosaic model
$(b)$ $P$. Maheshwari	$(ii)$ First recombinant plasmid
$(c)$ Cohen and Boyer	$(iii)$ Haploid culture
$(d)$ Singer and Nicolson	$(iv)$ Rust disease

What do '$X$' and '$Y$' represent in the given figure of a stirred-tank bioreactor?

Match the contents of List-$I$ with List-$II$:

List-$I$	List-$II$
$A$. Bioreactors	$(i)$ Insulin produced by rDNA technology
$B$. Downstream processing	$(ii)$ Vessels which convert raw material into specific product
$C$. Recombinant protein	$(iii)$ Detect mutated genes in suspected cancer patient
$D$. $PCR$	$(iv)$ Involves separation and purification

Consider the following statements:
$I.$ Recombinant $DNA$ technology,popularly known as genetic engineering,is a stream of biotechnology which deals with the manipulation of genetic material by man in vitro.
$II.$ $pBR322$ is the first artificial cloning vector developed in $1977$ by Bolivar and Rodriguez from $E. coli$ plasmid.
$III.$ Restriction enzymes belong to a class of enzymes called nucleases.
Which of the statements given above are correct?