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(C) The secretion of $GnRH$ (Gonadotropin-Releasing Hormone) from the hypothalamus is regulated by the feedback mechanism of ovarian hormones.In femal

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estrogen and progesterone

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(C) The secretion of $GnRH$ (Gonadotropin-Releasing Hormone) from the hypothalamus is regulated by the feedback mechanism of ovarian hormones.In females,the pulse frequency of $GnRH$ is primarily controlled by the circulating levels of estrogen and progesterone.Estrogen exerts both positive and negative feedback on the hypothalamus and anterior pituitary,while progesterone primarily exerts negative feedback,especially during the luteal phase of the menstrual cycle,to modulate the frequency of $GnRH$ pulses.

Changes in $GnRH$ pulse frequency in females is controlled by circulating levels of

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