Choose the incorrect sentence.

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(D) The correct answer is $D$. $1$. Ribozymes are indeed $RNA$ molecules that possess catalytic activity,so option $A$ is correct. $2$. Enzymes are pr

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Living state is possible without metabolism.

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(D) The correct answer is $D$. $1$. Ribozymes are indeed $RNA$ molecules that possess catalytic activity,so option $A$ is correct. $2$. Enzymes are proteins that fold into complex $3D$ structures,including tertiary and sometimes quaternary levels,so option $B$ is correct. $3$. In an energy profile diagram,if the potential energy of the product $(P)$ is lower than the substrate $(S)$,energy is released,characterizing an exothermic reaction,so option $C$ is correct. $4$. Metabolism is the sum total of all chemical reactions occurring in a living organism. The living state is defined by a constant turnover of biomolecules through metabolic pathways; therefore,the living state is impossible without metabolism. Thus,option $D$ is incorrect.

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