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(C) The symptoms described (obesity,low plasma $Na^+$,high $K^+$,and increased blood pressure) are characteristic of $Addison's$ disease,which is caus

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Cortisol

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(C) The symptoms described (obesity,low plasma $Na^+$,high $K^+$,and increased blood pressure) are characteristic of $Addison's$ disease,which is caused by the deficiency of glucocorticoids and mineralocorticoids,primarily $Cortisol$ and $Aldosterone$. $Cortisol$ is a glucocorticoid that plays a vital role in glucose metabolism,immune response,and maintaining blood pressure. Deficiency of $Cortisol$ leads to an inability to maintain electrolyte balance,resulting in hyponatremia (low $Na^+$) and hyperkalemia (high $K^+$),along with metabolic disturbances that can lead to weight changes and cardiovascular issues.

Deficiency of which of the following causes obesity,low plasma $Na^+$,high $K^+$ and increased blood pressure?

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