Desmosomes or Tonofibrils are

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(C) Desmosomes are specialized intercellular junctions that provide strong adhesion between cells. They are formed by the interaction of transmembrane

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Formed in cytoplasm by the union of plasma membrane

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(C) Desmosomes are specialized intercellular junctions that provide strong adhesion between cells. They are formed by the interaction of transmembrane proteins (like cadherins) with the cytoskeleton (specifically intermediate filaments or tonofilaments) within the cytoplasm. These structures are essential for maintaining the structural integrity of tissues subjected to mechanical stress,such as the skin and cardiac muscle. Therefore,they are associated with the plasma membrane and the cytoplasmic cytoskeleton.

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