During oxygen transport,the oxyhaemoglobin at the tissue level liberates oxygen to the cells because

Which factors in the tissues favor the dissociation of oxygen from oxyhaemoglobin?

How much $CO_2$ is added to every $100\,ml$ of blood by the tissues (in $,ml$)?

Given below are two statements:
Statement $I$: The relationship between $HbO_2$ saturation and oxygen tension $(pO_2)$ is called the oxygen-dissociation curve.
Statement $II$: The oxygen dissociation curve shifts towards the right due to a decrease in $ppCO_2$ and a decrease in temperature.
In the light of the above statements,choose the most appropriate answer from the options given below.

Which of the following combines irreversibly with blood haemoglobin?

Select the correct option for the transport of $CO_2$ in the blood:
$RBCs \quad Plasma \quad Bicarbonate$