If both parents are carriers for thalassemia, | vedclass

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Question

(B) Thalassemia is an autosomal recessive disorder. Let '$A$' represent the dominant normal allele and '$a$' represent the recessive mutant allele.Car

Vedclass · Accepted Answer

$25\%$

Vedclass · Answer

(B) Thalassemia is an autosomal recessive disorder. Let '$A$' represent the dominant normal allele and '$a$' represent the recessive mutant allele.Carrier parents have the genotype '$Aa$'.When two carrier parents $(Aa 	imes Aa)$ reproduce,the possible genotypes of the offspring are determined by a Punnett square:- $AA$ (Normal child): $25\%$- $Aa$ (Carrier child): $50\%$- $aa$ (Affected child): $25\%$Therefore,the probability of having an affected child $(aa)$ is $25\%$.

If both parents are carriers for thalassemia,which is an autosomal recessive disorder,what are the chances of pregnancy resulting in an affected child?

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