In sickle cell anaemia,glutamic acid is repla | vedclass

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Question

(C) Sickle cell anaemia is a point mutation caused by the substitution of a single nucleotide in the gene for the $\beta$-globin chain of haemoglobin.

Vedclass · Accepted Answer

$GAG$

Vedclass · Answer

(C) Sickle cell anaemia is a point mutation caused by the substitution of a single nucleotide in the gene for the $\beta$-globin chain of haemoglobin.In the normal haemoglobin gene,the codon $GAG$ codes for glutamic acid at the sixth position of the $\beta$-globin chain.Due to a mutation,$GAG$ is replaced by $GUG$,which codes for valine.Therefore,$GAG$ is the codon for glutamic acid,and $GUG$ is the codon for valine.Both $GAA$ and $GAG$ code for glutamic acid,but in the context of the sickle cell anaemia mutation,$GAG$ is the specific codon that undergoes substitution to $GUG$.

In sickle cell anaemia,glutamic acid is replaced by valine. Which of the following codes for glutamic acid?

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