In allergy and urticaria,the local arterioles | vedclass

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(D) During an allergic reaction,mast cells are activated and release chemical mediators into the surrounding tissues.One of the primary chemicals rele

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Histamine

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(D) During an allergic reaction,mast cells are activated and release chemical mediators into the surrounding tissues.One of the primary chemicals released by mast cells is $Histamine$.$Histamine$ acts as a potent vasodilator,meaning it causes the local arterioles (small blood vessels) to dilate (widen).This dilation increases blood flow to the affected area,which contributes to the redness,swelling,and itching associated with allergic reactions like urticaria (hives).

In allergy and urticaria,the local arterioles dilate due to an increased substance released from mast cells,called:

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