In Huntington's disease,the unaffected person | vedclass

Name: Exam Paper Generator | JEE NEET Paper Generator | Vedclass
Brand: Vedclass
Rating: 5 (35 reviews)

Question

(B) Huntington's disease is an autosomal dominant disorder. In an autosomal dominant pedigree,an affected individual must have at least one affected p

Vedclass · Accepted Answer

either person $6$ or $7$ should have the disease,if individual $11$ shows the disease.

Vedclass · Answer

(B) Huntington's disease is an autosomal dominant disorder. In an autosomal dominant pedigree,an affected individual must have at least one affected parent.In the given pedigree,individual $11$ is affected (represented by a filled circle). Since the disease is autosomal dominant,at least one of her parents ($6$ or $7$) must also be affected (represented by a filled symbol).However,in the pedigree,both individuals $6$ and $7$ are unaffected (represented by empty symbols). Therefore,this pedigree is erroneous because it violates the rule of autosomal dominant inheritance.

In Huntington's disease,the unaffected persons are homozygous for normal allele $h$. The following pedigree is erroneous because:

Similar Questions

Which of the following disorders is not hereditary?

Pedigree analysis is very important in human beings because

$A$ normal woman,whose father was colourblind,marries a normal man. What kinds of children can be expected and in what proportion?

What is pedigree analysis? Suggest how such an analysis can be useful.

Mention any two autosomal genetic disorders with their symptoms.

Vedclass Test Series

Exam Paper Generator

Online Exam Module