Koch's postulates are not applicable to

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(B) Koch's postulates are a set of criteria designed to establish a causative relationship between a microbe and a disease.$1$. The microorganism must

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Leprosy

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(B) Koch's postulates are a set of criteria designed to establish a causative relationship between a microbe and a disease.$1$. The microorganism must be found in abundance in all organisms suffering from the disease, but should not be found in healthy organisms.$2$. The microorganism must be isolated from a diseased organism and grown in pure culture.$3$. The cultured microorganism should cause disease when introduced into a healthy organism.$4$. The microorganism must be re-isolated from the inoculated, diseased experimental host and identified as being identical to the original specific causative agent.Leprosy, caused by $Mycobacterium$ 	ext{ leprae}, is an exception because it cannot be grown in a cell-free culture medium (pure culture), which violates the second postulate of Koch.

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