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(A) The chromosomal abnormalities are matched as follows:$(1)$ Patau's syndrome is caused by trisomy of the $13^{th}$ chromosome ($46 + 1 = 47$, $13^{

Vedclass · Accepted Answer

$1-C, 2-A, 3-D, 4-B$

Vedclass · Answer

(A) The chromosomal abnormalities are matched as follows:$(1)$ Patau's syndrome is caused by trisomy of the $13^{th}$ chromosome ($46 + 1 = 47$, $13^{th}$ chromosome), which corresponds to $(C)$.$(2)$ Klinefelter's syndrome is characterized by an extra $X$ chromosome in males $(44 + XXY = 47)$, which corresponds to $(A)$.$(3)$ Down's syndrome is caused by trisomy of the $21^{st}$ chromosome ($46 + 1 = 47$, $21^{st}$ chromosome), which corresponds to $(D)$.$(4)$ Turner's syndrome is characterized by the loss of an $X$ chromosome in females $(44 + X = 45)$, which corresponds to $(B)$.Therefore, the correct matching is $1-C, 2-A, 3-D, 4-B$.

List-$I$ (Syndrome)	List-$II$ (Chromosomal abnormality)
$(1)$ Patau's syndrome	$(A)$ $44 + XXY = 47$
$(2)$ Klinefelter's syndrome	$(B)$ $44 + X = 45$
$(3)$ Down's syndrome	$(C)$ $46 + 1 = 47$, $13^{th}$ chromosome
$(4)$ Turner's syndrome	$(D)$ $46 + 1 = 47$, $21^{st}$ chromosome

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