Myosin head separates from actin when:

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(D) During the muscle contraction cycle,the myosin head remains bound to the actin filament in a cross-bridge state. When a new molecule of $ATP$ bind

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When $ATP$ attached to myosin head

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(D) During the muscle contraction cycle,the myosin head remains bound to the actin filament in a cross-bridge state. When a new molecule of $ATP$ binds to the myosin head,the affinity of the myosin head for actin decreases significantly. Consequently,the myosin head detaches from the actin filament. Therefore,the separation occurs when $ATP$ attaches to the myosin head.

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