(A) The genome of $E. coli$ $(Escherichia coli)$ consists of approximately $4.6 \times 10^6$ base pairs. Based on genomic sequencing and analysis,it i

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(A) The genome of $E. coli$ $(Escherichia coli)$ consists of approximately $4.6 \times 10^6$ base pairs. Based on genomic sequencing and analysis,it is estimated to contain about $4000$ to $4500$ genes. Therefore,$4000$ is the closest approximation among the given options.