'One gene one enzyme hypothesis' was given by

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(B) The 'One gene one enzyme hypothesis' was proposed by George Beadle and Edward Tatum in $1941$ (awarded Nobel Prize in $1958$).This hypothesis was

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Beadle and Tatum

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(B) The 'One gene one enzyme hypothesis' was proposed by George Beadle and Edward Tatum in $1941$ (awarded Nobel Prize in $1958$).This hypothesis was based on their experiments with nutritional mutations in the pink bread mold, $Neurospora crassa$.They demonstrated that specific genes are responsible for the production of specific enzymes, which catalyze metabolic reactions.

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