The reaction is given as follows:Ph-CO-N(CH_3 | vedclass

Name: Exam Paper Generator | JEE NEET Paper Generator | Vedclass
Brand: Vedclass
Rating: 5 (35 reviews)

Question

(B) The starting material is $N$-methoxy-$N$-methylbenzamide (Weinreb amide).Weinreb amides react with Grignard reagents $(RMgX)$ to form ketones afte

Vedclass · Accepted Answer

$Ph-CO-CH_3$

Vedclass · Answer

(B) The starting material is $N$-methoxy-$N$-methylbenzamide (Weinreb amide).Weinreb amides react with Grignard reagents $(RMgX)$ to form ketones after hydrolysis.In this reaction,$N$-methoxy-$N$-methylbenzamide reacts with $2$ equivalents of $CH_3MgBr$.The first equivalent of $CH_3MgBr$ attacks the carbonyl carbon to form a stable tetrahedral intermediate,which prevents further reaction with the Grignard reagent.Upon acid hydrolysis $(H_3O^+)$,this intermediate decomposes to form acetophenone $(Ph-CO-CH_3)$.Therefore,the product $(P)$ is acetophenone $(Ph-CO-CH_3)$.

The reaction is given as follows:
$Ph-CO-N(CH_3)(OCH_3) + 2CH_3MgBr \xrightarrow{H_3O^+} (P)$
Product $(P)$ is:

Similar Questions

Consider the following reaction, and choose the correct option.
$Toluene \xrightarrow[ii. H_3O^+]{i. CrO_2Cl_2, CS_2} P$

Which of the following methods can be used to prepare acetophenone?

In the given reactions,identify the reagent $A$ and reagent $B$.

Conversion of esters to aldehydes can be accomplished by

Identify the name of the following reaction:
$Toluene + CrO_2Cl_2$ $\xrightarrow{CS_2} \text{complex}$ $\xrightarrow{H_3O^+} \text{Benzaldehyde}$

Vedclass Test Series

Exam Paper Generator

Online Exam Module

The reaction is given as follows:$Ph-CO-N(CH_3)(OCH_3) + 2CH_3MgBr \xrightarrow{H_3O^+} (P)$Product $(P)$ is: