Statement -I : Iodothyronines can cross the p | vedclass

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(C) Iodothyronines (thyroid hormones like $T_3$ and $T_4$) are lipophilic in nature.Because they are lipophilic,they can easily cross the lipid bilaye

Vedclass · Accepted Answer

Statement $-I$ is correct but Statement $-II$ is incorrect.

Vedclass · Answer

(C) Iodothyronines (thyroid hormones like $T_3$ and $T_4$) are lipophilic in nature.Because they are lipophilic,they can easily cross the lipid bilayer of the plasma membrane of target cells.Once inside the cell,they bind to intracellular receptors (specifically nuclear receptors) to regulate gene expression.Therefore,Statement $-I$ is correct.Since iodothyronines bind to intracellular receptors,they do not require receptors on the plasma membrane.Therefore,Statement $-II$ is incorrect.

Column-$I$	Column-$II$
$P$. Peptide, polypeptide, protein hormones	$I$. Epinephrine
$Q$. Steroids	$II$. Thyroid hormones
$R$. Iodothyronines	$III$. Cortisol, testosterone, estradiol, progesterone
$S$. Amino acid derivatives	$IV$. Hormones of pancreas, pituitary, and hypothalamus

Statement $-I :$ Iodothyronines can cross the plasma membrane of a cell.
Statement $-II :$ Receptors of iodothyronines are present on the plasma membrane.

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Statement $-I :$ Iodothyronines can cross the plasma membrane of a cell.Statement $-II :$ Receptors of iodothyronines are present on the plasma membrane.