Thalassemia and Sickle cell anaemia are cause | vedclass

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Question

(D) Step $1$: Sickle cell anaemia is a qualitative defect where a single amino acid substitution ($Glu$ to $Val$ at the $6^{th}$ position of the $\bet

Vedclass · Accepted Answer

Thalassemia is due to less synthesis of globin molecules.

Vedclass · Answer

(D) Step $1$: Sickle cell anaemia is a qualitative defect where a single amino acid substitution ($Glu$ to $Val$ at the $6^{th}$ position of the $\beta$-globin chain) occurs, leading to abnormal haemoglobin structure.Step $2$: Thalassemia is a quantitative defect where there is reduced or absent synthesis of one of the globin chains ($\alpha$ or $\beta$) of the haemoglobin molecule.Step $3$: Comparing the options, option $(D)$ correctly identifies that Thalassemia is caused by reduced synthesis of globin molecules.

Thalassemia and Sickle cell anaemia are caused by problems in globin molecule synthesis. Select the correct statement.

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