The disease resulting from prolonged clotting | vedclass

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Question

(A) The disease caused by the deficiency of plasma thromboplastin component $(PTC)$,also known as Factor $IX$,is called Christmas disease or Haemophil

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Christmas disease

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(A) The disease caused by the deficiency of plasma thromboplastin component $(PTC)$,also known as Factor $IX$,is called Christmas disease or Haemophilia $B$.This condition leads to a prolonged blood clotting time because $PTC$ is essential for the formation of the thromboplastin complex in the intrinsic pathway of the coagulation cascade.While Haemophilia $A$ is caused by a deficiency of Factor $VIII$,Christmas disease is specifically associated with the lack of $PTC$ (Factor $IX$).

Column-$I$ (Blood group)	Column-$II$ (Antibody)
$A$. $A$	$P$. $b$
$B$. $B$	$Q$. $a$
$C$. $AB$	$R$. $nil$
$D$. $O$	$S$. $a$ and $b$

The disease resulting from prolonged clotting time due to the lack of plasma thromboplastin component $(PTC)$,which is necessary for the formation of thromboplastin,is:

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