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Which of the following statement$(s)$ is(are) true?
$(1)$ Oxidation of glucose with bromine water gives gluconic acid.
$(2)$ The two six-membered cyclic hemiacetal forms of $D-(+)-$glucose are called anomers.
$(3)$ Hydrolysis of sucrose gives dextrorotatory glucose and laevorotatory fructose.
$(4)$ Monosaccharides cannot be hydrolysed to give polyhydroxy aldehydes and ketones.

Identify the correct set of stereochemical relationships amongst the following monosaccharides $(I)-(IV)$:

Match Column-$I$ with Column-$II$ and select the correct option.
Column-$I$ Column-$II$
$(i)$ Antiberiberi factor $(A)$ Vitamin $C$
$(ii)$ Pancreas $(B)$ Glycerides
$(iii)$ Palm oil $(C)$ Vitamin $B_1$
$(iv)$ $L(+)$-Ascorbic acid $(D)$ Insulin

Which of the following statements are correct?
a) In maltose,$C-1$ of one $\alpha-D$-glucose is linked to $C-4$ of second $\alpha-D$-glucose.
b) Quaternary structure of protein represents spatial arrangement of two or more polypeptide chains with respect to each other.
c) Nucleotide units in a nucleic acid are joined to each other through a phosphodiester linkage.
d) Abnormally low level of thyroxine leads to hypothyroidism.

Assertion : $DNA$ as well as $RNA$ molecules are found in the nucleus of a cell.
Reason : On heating,the enzymes do not lose their specific activity.

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