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(A) Palmitic acid is a $16$-carbon saturated fatty acid $(C_{16}H_{32}O_2)$.It undergoes $\beta$-oxidation,which involves $7$ cycles to produce $8$ mo

Vedclass · Accepted Answer

$130$

Vedclass · Answer

(A) Palmitic acid is a $16$-carbon saturated fatty acid $(C_{16}H_{32}O_2)$.It undergoes $\beta$-oxidation,which involves $7$ cycles to produce $8$ molecules of Acetyl-$CoA$,$7$ molecules of $FADH_2$,and $7$ molecules of $NADH$.Each Acetyl-$CoA$ enters the Citric Acid Cycle to produce $10$ $ATP$ ($3$ $NADH$,$1$ $FADH_2$,$1$ $GTP/ATP$). Total from $8$ Acetyl-$CoA$ = $8 	imes 10 = 80$ $ATP$.Each $FADH_2$ produces $1.5$ $ATP$ and each $NADH$ produces $2.5$ $ATP$.From $\beta$-oxidation: $7 	imes 1.5 = 10.5$ $ATP$ and $7 	imes 2.5 = 17.5$ $ATP$.Total $ATP = 80 + 10.5 + 17.5 = 108$ $ATP$.Subtracting $2$ $ATP$ used for activation of fatty acid to fatty acyl-$CoA$,the net yield is $106$ $ATP$.However,in many older textbooks,the calculation is based on $3$ $ATP$ per $NADH$ and $2$ $ATP$ per $FADH_2$,leading to $129$ or $130$ $ATP$. Given the options,$130$ is the standard answer.

The number of molecules of $ATP$ produced in the lipid metabolism of a molecule of palmitic acid is

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