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(D) The genetic code is read in triplets (codons). $A$ change in the reading frame (frameshift mutation) occurs when the number of nucleotides inserte

Vedclass · Accepted Answer

Deletion of $GGU$ from $7^{th}, 8^{th}$ and $9^{th}$ positions

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(D) The genetic code is read in triplets (codons). $A$ change in the reading frame (frameshift mutation) occurs when the number of nucleotides inserted or deleted is not a multiple of $3$.If $3$ nucleotides (or a multiple of $3$) are inserted or deleted,the reading frame remains unchanged,although one or more amino acids may be added or removed.In the given $mRNA$ sequence $5'-AAC-AGC-GGU-GCU-AUU-3'$,deleting $GGU$ (which consists of $3$ nucleotides) from the $7^{th}, 8^{th}$,and $9^{th}$ positions removes exactly one codon.This results in the loss of one amino acid,but the subsequent codons remain in the same reading frame.Therefore,option $D$ is the correct condition.

Under which of the following conditions will there be no change in the reading frame of the following $mRNA$: $5'-AACAGCGGUGCUAUU-3'$?

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