The Warburg effect is the:

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(A) Otto Warburg observed that high concentrations of $O_{2}$ inhibit the rate of photosynthesis in $C_{3}$ plants. This phenomenon is known as the Wa

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Inhibition of $C_{3}$-cycle by $O_{2}$

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(A) Otto Warburg observed that high concentrations of $O_{2}$ inhibit the rate of photosynthesis in $C_{3}$ plants. This phenomenon is known as the Warburg effect.It occurs because $O_{2}$ competes with $CO_{2}$ for the active site of the enzyme RuBisCo.When $O_{2}$ binds to RuBisCo,it initiates photorespiration ($C_{2}$-cycle) instead of the Calvin cycle ($C_{3}$-cycle),thereby reducing the efficiency of photosynthesis.Therefore,the Warburg effect is the inhibition of the $C_{3}$-cycle by $O_{2}$.

Column-$I$	Column-$II$
$(1)$ Molecule transport from chloroplast to peroxisome	$(p)$ Glycine
$(2)$ Molecule transport from peroxisome to mitochondria	$(q)$ Serine
$(3)$ Molecule transport from mitochondria to peroxisome	$(r)$ Glycerate
$(4)$ Molecule transport from peroxisome to chloroplast	$(s)$ Glycolate

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