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(C) The first recombinant $DNA$ molecule was constructed in $1973$ by Stanley Cohen and Herbert Boyer. They accomplished this by isolating an antibiot

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$1973$

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(C) The first recombinant $DNA$ molecule was constructed in $1973$ by Stanley Cohen and Herbert Boyer. They accomplished this by isolating an antibiotic resistance gene and linking it with a native plasmid of $Salmonella$ $typhimurium$. This recombinant plasmid was then successfully introduced (inoculated) into $E. coli$ using transformation techniques,marking the birth of modern biotechnology.

When was the first extra $DNA$ fragment successfully inoculated into $E. coli$ using a plasmid?

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