When you hold your breath,which of the follow | vedclass

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(D) The correct answer is $(d)$. When you hold your breath,the concentration of $CO_2$ in the blood increases because it is not being exhaled. This ri

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Rising $CO_2$ concentration

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(D) The correct answer is $(d)$. When you hold your breath,the concentration of $CO_2$ in the blood increases because it is not being exhaled. This rise in $CO_2$ concentration (hypercapnia) is the primary stimulus that acts on the central chemoreceptors in the medulla oblongata of the brain. These receptors detect the increase in $H^+$ ions resulting from the reaction of $CO_2$ with water,which triggers the respiratory centre to increase the rate and depth of breathing. While a decrease in $O_2$ (hypoxia) can also stimulate breathing via peripheral chemoreceptors,the rise in $CO_2$ is the most sensitive and immediate trigger for the urge to breathe under normal physiological conditions.

When you hold your breath,which of the following gas changes in blood would first lead to the urge to breathe?

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