(C) The $enolase$ enzyme, which catalyzes the conversion of $2-phosphoglycerate$ to $phosphoenolpyruvate$ during glycolysis, requires divalent metal i

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(C) The $enolase$ enzyme, which catalyzes the conversion of $2-phosphoglycerate$ to $phosphoenolpyruvate$ during glycolysis, requires divalent metal ions for its catalytic activity. $Magnesium$ $(Mg^{2+})$ is the essential cofactor that binds to the enzyme to stabilize the transition state and facilitate the reaction.