Which of the following statements are correct with reference to the packaging of the $DNA$ helix?
$(A)$ Histones are organized to form a unit of eight molecules called a histone octamer.
$(B)$ Histones are negatively charged basic proteins.
$(C)$ Histones are rich in the basic amino acid residues - lysine and arginine.
$(D)$ The negatively charged $DNA$ is wrapped around the positively charged histone octamer to form a nucleosome.
$(E)$ The packaging of chromatin at higher levels requires an additional set of proteins called non-histone chromosomal proteins.

  • A
    $A$, $C$, $D$, $E$
  • B
    $A$, $B$, $C$, $D$
  • C
    $B$, $C$, $D$, $E$
  • D
    $A$, $B$, $D$, $E$

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